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Research has shown that psychedelics may be useful in the treatment of various mental-health conditions, including post-traumatic stress disorder (PTSD) and depression. Now new methods of cultivation are making hallucinogenic mushrooms stronger, with their effects being felt by users faster and lasting longer.
Julian Mattucci, commonly referred to as God Emperor Myco, recently revealed that he had tried about 1.5g of Psilocybe subtropicalis mushrooms. This dosage, which is considerably lower than the amount normally required to have a significant trip, was potent enough to have him lying in bed for three to four hours. Mattucci later tested the mushrooms, discovering that a single batch contained nearly 5% psychedelic alkaloids. This was surprising, especially since mushrooms in the Psilocybe genus only contain 1% of these psychoactive alkaloids. Other species, including Psilocybe azurescens, are usually stronger, with some varieties in the Panaeolus genus being even stronger.
By using imperfect techniques, hobbyist cultivators have been able to heavily inbreed commonly consumed mushrooms such as Psilocybe Cubensis mushrooms over the years. The first spore prints of this particular mushroom were first brought to the United States from the Amazon by the McKenna brothers in the 1970s.
The founder of the Center for Mycological Analytics, Ian Bollinger, argues that Mount Everest has the strongest potency.
With mushroom cultivation becoming somewhat professional, mycologists are using informed practices to breed the plants, helping improve their potency and enhancing their genetic integrity. Genetic sequencing is playing a significant role in breeding these mushrooms, with tech advancements also allowing cells to be manipulated more easily during breeding.
Mushrooms of the Panaeolus genus are being explored as part of this growing trend, with some mushrooms of this type being more potent naturally than those in other families. Matucci expects that through cultivation, the potency of mushrooms under this genus will increase four-fold.
One ecologist, Sam Gandy, believes that patients with gastrointestinal issues who may find it hard to ingest psilocybin mushrooms may benefit from these mushroom cultivars, however. While this is a plus, the growing availability of potent mushrooms may cause individuals to accidentally consume more than they had wanted to, heightening the risk of distressing trips.
It doesn’t help that safe dosing instructions are lacking, which makes it harder for individuals to gauge what they will need for a trip. Overall, consumers may benefit from doing their own research on the mushrooms, even talking to experts when possible, prior to undergoing a psychedelic trip.
The uncertainties surrounding the psychedelic mushrooms grown in nonmedical settings make a strong case for the work that different companies, such as Seelos Therapeutics Inc. (NASDAQ: SEEL), are doing to develop standardized medicines from these substances so that patients in need can access therapeutics overseen by competent regulatory bodies, including the FDA.
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