The commercialization of medical and edible cannabis are limited by the current delivery and consumption methods. The plant oil extracts are hydrophobic in nature, which limits their application in water-based systems. Furthermore, cannabis oils have a very low oral bioavailability. Nanotechnology is a promising strategy address theses issues. There are two different approaches to produce nano-sized oil droplet in water phase. A mechanical approach in which high shear or high intensity ultrasound waves are used to breakdown oil droplets to 100-500 nm. However, this approach is energy-intensive and the finished products are not stable in long term. Microemulsions are the most advanced approach for creating stable, nano-sized droplets (10-100 nm), water-soluble and bioavailable products. A team of U of T researchers have developed a delivery system made with FDA-approved ingredients that can enhance the absorption of drugs 4 folds. Therefore, 1/4 drug per dose is needed compared to conventional methods and hence it is a cost-saving strategy. The platform can also be used to extract cannabis oil from the plant tissues much more effective than using the traditional solvents.