Jazz Pharmaceuticals receives Health Canada approval for Epidiolex for the treatment of seizures associated with three rare forms of epilepsy

Jazz Pharmaceuticals receives Health Canada approval for Epidiolex for the treatment of seizures associated with three rare forms of epilepsy

These three conditions are rare and severe forms of epilepsy that cause multiple seizure types, which are generally resistant to treatment.

“Living with LGS, Dravet syndrome or TSC is very difficult. It means enduring recurring seizures every day. This presents a challenging and isolating experience for individuals living with these conditions to experience and places a great deal of stress on caregivers who witness the seizures,” says Laura Dickson, president of the Canadian Epilepsy Alliance. “This approval encourages hope and optimism for this community. The priority now becomes ensuring those living with these conditions have equitable and timely access to promising treatment options.”

Epidiolex is a prescription medicine, administered as an oral solution. Cannabidiol, the active ingredient in Epidiolex, is a cannabinoid that naturally occurs in the Cannabis sativa L. plant.

Advertisement

“While there are many anti-seizure medications available for different epilepsies, as rare and severe forms of childhood-onset epilepsies, LGS, Dravet syndrome and TSC have limited approved therapies and are often treatment-resistant. This makes these conditions extremely difficult to treat,” says Linda Huh, paediatric epileptologist at BC Children’s Hospital and the University of British Columbia. “The Health Canada approval of Epidiolex is significant news for a patient population with a critical unmet need, providing us with a robustly studied treatment option.”

The Health Canada approval was based on results from five double-blind, randomized, placebo-controlled Phase 3 clinical trials, with a total of 939 LGS, Dravet syndrome, or TSC patients enrolled, making it one of the largest global clinical trial programs to date in rare refractory epilepsy syndromes.

“The approval of Epidiolex is an important development for individuals living with specific rare epilepsies, their families, and clinicians across Canada, providing a new treatment option for those living with LGS, Dravet syndrome or TSC,” said Paul Petrelli, General Manager of Jazz Pharmaceuticals Canada Inc. “This decision affirms the potential of cannabinoid-based medicines for those living with epilepsy. It also reaffirms Jazz’s commitment to bringing forward new therapeutic options for Canadians living with rare and debilitating neurological conditions.”

The onset of LGS typically occurs between ages of three to five years and can be caused by a number of conditions, including brain malformations, severe head injuries, central nervous system infections, and genetic neuro-degenerative or metabolic conditions. The estimated prevalence LGS is approximately three to 28 in 100,000 people.

Dravet syndrome is a severe infantile-onset and highly treatment-resistant developmental and epileptic encephalopathy frequently associated with genetic mutations in the sodium channel gene SCN1A. Research suggests the condition affects between one in 20,000 to one in 40,000 people. Three to eight per cent of children who have their first seizure by 12 months old may have Dravet syndrome.

TSC is a condition that causes mostly benign tumours to grow in vital organs of the body, including the brain, skin, heart, eyes, kidneys and lungs, and in which, epilepsy is one of the most common neurological manifestations. TSC affects as many as one million individuals worldwide, and more than 60 per cent of individuals with TSC do not achieve seizure control with standard treatments.

This decision represents the authorization of Jazz Canada’s first approved cannabinoid-based medicine and underlines the company’s commitment to developing, researching, and commercializing regulatory approved cannabinoid-based medicines.

Following the Health Canada approval, Jazz will work with the relevant stakeholders in Canada, to secure reimbursement for eligible patients.

In addition to Canada, Jazz has received approval for the cannabidiol oral solution Epidiolex (also known as Epidyolex in the European Union) for the treatment of seizures associated with LGS, Dravet Syndrome or TSC, for certain patient populations, in 36 countries other countries, including the U.S., EU, Great BritainAustraliaNew ZealandIsrael and Switzerland.

Cannabis sales declined in September

Cannabis sales declined in September

November 24, 2023 | Staff

Retail cannabis sales in Canada declined 4.9% in September, from an August high of $589 million to $560 million.

Sales increased month-by-month from February 2023 to August, following a post-Christmas decline from a previous peak of $511 million in December 2022. 

Cannabis sales in Canada have continued to increase annually, despite periodic declines. While these declines in sales are generally after Christmas, smaller drops have also occurred just before December. 

This current decline occurred alongside a downturn for other parts of the Canadian economy. Core retail sales for all of Canada—excluding gasoline stations, fuel vendors, and motor vehicle and parts dealers—were down 0.3% in September.  

Data on retail trade for October will be released on December 21, 2023. 

Wholesale trade for cannabis also declined from a peak in August of 288 million to $261 million. The previous high was $260 million in September 2022.

The number of retail stores across Canada also continues to grow, although the pace has slowed considerably compared to the first four years of legalization. As of October 2023, there were 3,654 cannabis stores in Canada, excluding provincial online stores, an increase of 14 stores from September.

  • British Columbia: 513 public and private stores either open or “coming soon”
  • Alberta: 749
  • Saskatchewan: 176
  • Manitoba: 194, 112 of which are in Winnipeg 
  • Ontario: 1,770 as authorized to open 
  • Quebec: 98
  • New Brunswick: 25 public stores, plus seven private stores and six farmgate stores for a total of 37
  • Nova Scotia: 49
  • PEI: 4 
  • Newfoundland and Labrador: 49
  • Northwest Territories: 6 brick-and-mortar locations, plus 1 private online store
  • Nunavut: 1
  • Yukon: 6

Lasqueti cannabis grower working to preserve the island’s unique cannabis culture

Lasqueti cannabis grower working to preserve the island’s unique cannabis culture

A micro cultivator and processor is working to keep the cannabis culture alive on BC’s Lasqueti Island, located just east of Vancouver Island in the Strait of Georgia. 

Lasqueti Cannabis Co., a passion project run by Kathy Bond and her partner Keith Morris, was licensed in October 2022 and had its first crops on the shelves in BC one year later.

The island itself has a storied history of cannabis production. It was once referred to as a “mecca” for medical cannabis production by the RCMP and is known for helping develop unique cultivars, including Lasqueti Lemon Haze and Lasqueti Kush.

Bond, who operates as the RPIC for the micro producer, also oversees 13 employees, all island residents who have deep connections to that storied past. 

Although she says some of the culture of the island has changed since COVID-19, with some long-time residents moving off the remote island, she sees Lasqueti Cannabis as a way to help keep some of that history alive and profitable for those wanting to still live there. 

“It’s a big job creator for the island. We’re putting the island back to work doing what they do best and what they have become famous for over the years. All our employees are full-time island residents who have been growing cannabis their whole lives.”

Lasqueti Cannabis’ Stay Puff nears harvest

That protection of the island’s cannabis culture extends to some of those unique Lasqueti Island cannabis cultivars, too, continues Bond. They brought in around 150 unique varieties of cannabis in the form of 1,500 seeds and are currently working on some as-yet-to-be-named cultivars she’s particularly excited about based on their unique aromas.

Although these aren’t always the high-THC that the market currently demands, she says she’s hopeful that consumers can recognize there’s more to quality than that one number. 

“We want to prove to the world that THC isn’t what makes good cannabis,” Bond adds.

Island life makes things move a lot slower, though. Lasqueti has no outside power, and residents rely on a mixture of generators and alternative forms of energy. The one ferry that services the island is walk-on only, and all cannabis they deliver to the LDB or send to retailers via direct delivery has to be escorted on the ferry. 

As a small business, she says she still does much of the work herself, even personally delivering their first shipment to the LDB’s distribution centre in Richmond, across two ferry routes. 

“We do what we have to do, and we’re used to working together as a community.”

Ideally, Bond and Morris want to have a retail store of some kind on the island, as either a farmgate licence or a stand-alone store, to service not only the year-round locals but also the other thousand or so summer residents and tourists who come through the island’s port “city” annually. 

“We know how to grow good cannabis, and there are some great strains coming on down the line,” says Bond. “We have the people, we have the knowledge, we have the strains. We just have to get our message out there to the world to let them know who we are.” 

Lasqueti Cannabis’ Gas Truffle and Apricot Stomper are available through the LDB’s central distribution, and their Friendly Bear and Stay Puff are available through direct delivery.

Kathy Bond and Keith Morris with Tommy Chong at a recent industry event.

Calgary Police investigating string of cannabis store robberies

Calgary Police investigating string of cannabis store robberies

Calgary Police confirm they are investigating a string of recent armed robberies in the city.

Police say it is believed that the same suspects are responsible for each of these robberies. In each incident, police say the suspects fled with an undisclosed amount of cash and cannabis products from the stores.

In a press release, police say the first event occurred around midnight on Wednesday, November 15, when they were called to the Four20 cannabis store in the south west of the city for an armed robbery. Suspects were gone by the time police arrived. Four20 has more than 30 locations in Calgary.

A week later on Wednesday, November 22, 2023, again at around midnight, police received reports of an armed robbery. The location this time was the Dank Cannabis Weed Dispensary Parkdale in the city’s north west. Dank has three locations in Calgary.

The suspects again fled the store prior to the arrival of police and were believed to be driving a stolen vehicle.  

Later that day, police were called for reports of a third armed robbery this time at a different Four20 location in Calgary’s south west. Police say it is believed that three suspects entered the store and brandished a gun and a knife.

Image via Google Maps

Police are working closely with business staff to obtain and review evidence. No suspects are in custody at this time. 

On November 22, the owner of two cannabis stores in the Calgary area noted the robberies and the aggressive nature of the robbers, including reports of employees being zip-tied. 

Robberies and burglaries of cannabis stores are not uncommon, and stores in Calgary have been previously targeted . Cannabis growers and processors have not been immune, either. Earlier this year at least two cannabis producers in BC’s Lower Mainland were the victims of early-morning burglaries.

Alberta recently repealed its rule requiring stores to have window coverings which retailers said made their employees less safe in the instance of such incidents.

Featured image of an armed robbery at a cannabis store in Calgary in 2021

Related Articles

The Spigot

The Spigot

The Good Citizen

The Spigot

The decline of music culture in the digital age.

@thegoodcitizen

Dumb and silent we are being led, like sheep to the slaughter.

Music is a higher revelation than all wisdom and philosophy.

— Ludwig Von Beethoven

Why do I add music to the end of every post?

Discussions of musical evolution often reflect generational differences and evolving tastes rather than objective apexes or declines in artistic creativity or cultural value related to civilizational ascendancy or decay.

To reduce music, and indeed all art to “a matter of individual taste” is to ignore the wider implications of the collective consumption of culture and the powerful and connective experiences music in particular can impart to a society.

To deny a connection between the popular tastes of music in a given epoch, its evolution through different periods influenced by respective triumphs and turmoil, and the arc of ascendancy or decline of a given civilization would ignore obvious signs symbolically expressed lyrically or musically.

The quickening of cultural decline that seems to be the order of this era, is often expressed musically as decadence, debauchery, nihilism, and moral decay. But if recent history is any barometer, there is a specific point in time that appears to have ushered in the decline of popular music, and it may be connected to several emerging techno-social phenomena related to musical production, distribution, and consumption.

Before we trace those lines toward that point, let’s first explore some historical patterns to gain some evolutionary insights that might offer both clarity and perspective.

The rise of popular music across the West, from the great classical music of Europe from the seventeenth to nineteenth centuries, to the rise of Blues, Jazz, Rhythm and Blues and Rock & Roll in the United States and Britain, signaled an evolving and transformative artistic apex that, a few lulls and voids excepted, consistently delivered profound emotive auditory experiences at a cultural level.

The relation of art and culture to the rise and fall of civilizations is well documented. In the panorama of history, music, art, and architecture have not merely been expressions of culture, but have also mirrored the spirit of their times, often heralding the rise or signaling the decline of civilizations.

The enduring pillars and temples of Ancient Greece, epitomized by the Parthenon, stand as testaments to the zenith of a civilization dedicated to the pursuit of beauty, order, symmetry, and proportion. This architectural grandeur mirrored the societal values of democracy, philosophy, and a nascent scientific understanding that characterized the Golden Age of Athens.

Contrast the classical beauty of Ancient Greece with the degrading and intentionally demoralizing simplicity of totalitarian societies. Communist architecture, especially the Brutalist style proliferated throughout the Eastern Bloc, stands as a stark symbol of the ideologies that shaped it. Devoid of innovative spirit, frivolity, and human scale, with a focus on raw concrete and functional form, it epitomized the state’s overpowering reach into the lives of its citizens. The colossal, austere buildings symbolized concrete edicts of power, designed to dwarf the individual and suppress any spark of rebellion or creative dissent. These buildings were functional in utility, but metaphorically they were monolithic declarations of a society that traded aesthetic beauty for homogeneity of thought and behavioral control.

Creativity and architectural innovation were not just stifled but were considered superfluous or even a threat, as they represented a past that had to be erased. The pervasive sameness of Brutalist structures across the Communist world mirrored the enforced equality where individualism and personal freedom were curtailed, and traditional or classical influences forbidden. They were the structural representations of an oppressive system, their very design anathema to aesthetics, attractiveness, and imagination.

Springsteen’s opening remarks in German, “I’m not here for or against any government. I’ve come to play rock’n’roll for you in the hope that one day all the barriers will be torn down,” set the tone for the event. Songs like “Chimes of Freedom” and “Born to Run” became anthems for the audience, emphasizing themes of liberation and escape from communist oppression.

What is the First Viennese School, and why do classical music people say it? - Classic FM

Moving from the contrasting artistic cultures of two opposing civilizations into the realm of music, the Baroque era brought forth a complexity and grandiosity that echoed the absolute monarchies of its time. Composers like Johann Sebastian Bach and George Frideric Handel composed works that were complex and magnificent, often commissioned by and performed in the courts of the German States and England. Their music, rich in emotional depth and structural intricacy, resonated with the splendor of the architectural marvels of their time, such as the Baroque palaces of Potsdam and Oxford. These compositions, much like the grand edifices that housed their premieres, were a testament to the cultural ambitions and the elevated status of their noble patrons.

The Church was still a prominent influence on musical composers of the time. In the role of patron, the Church commissioned works while simultaneously providing a crucial performance space with stellar acoustics, shaping the sound of sacred music, and creating an environment where the auditory experience was as much a part of worship as the liturgy itself.

In contrast, the Romantic period of the 19th century was marked by a musical revolution that sought to emancipate emotions from rigid rules of social conformity and highlight the individual. Composers such as Ludwig van Beethoven broke through the structured elegance of the Classical era to unleash a passionate and often tumultuous expression of the self and the sublime. This was music that sought to reflect and amplify the human spirit in an age that was grappling with the transformative consequences of enlightenment thinking, and economic growth through the Industrial Revolution, as the peoples of Europe began to question the legitimacy of hereditary monarchies that were dominant for the prior millennia.

Do You Speak Jazz? Jazz Slang Glossary – Berklee City Music Network

The classical era gave way to new forms of musical expression, with new instruments capturing sounds for innovative genres. Amidst the tapestry of cultural expression, the blues emerged as a raw and poignant articulation of the Black experience in the Deep South of the United States. Born from the fields and the hardships of slavery and segregation, the blues was a confluence of African rhythms and European harmonic structures, encapsulating the grind of a lost and outcast community. The melancholic twang of the blues guitar and the soulful depth of its vocals became the musical embodiment of the sorrow and hope of a singular common struggle. The genre was a profound vehicle for emotional connection and storytelling that would influence future popular genres.

Jazz, which sprouted from the seeds of the blues, soon blossomed into an eclectic and sophisticated language of music. It became synonymous with the Roaring Twenties and the defiant exuberance of the post-World War I era. In cities like New Orleans, Kansas City, and Chicago, jazz echoed the pulse of a changing America, with its improvisational nature capturing the era’s innovative spirit and the arrival and chaos of modernity. The syncopated rhythms and brassy serenades of jazz mirrored society in the throes of rapid industrialization and urbanization, offering a soundtrack to the turbulence and complexities of the evolving American psyche. Jazz was a cultural phenomenon that challenged often stifling social norms and encouraged a spirit of rebellion through improvisation and exploration.

Music of The 1950s by DavisTrousdale on DeviantArt

The arrival of rock and roll in the 1950s conceived from the womb of Rhythm and Blues continued this legacy of music as a reflection of societal shifts. Rock and roll was the sonic emblem of youthful insubordination and a burgeoning counterculture. Artists like Elvis Presley, Fats Domino, and Chuck Berry became icons, their music resonating with the independent and economically vibrant rise of the middle-class youth of the postwar generation. Rock and roll music was inherently intertwined with the era’s social issues, from civil rights to the questioning of traditional authority and social conformity.

Its infectious rhythms and primal energy embodied the teenage zeitgeist, symbolizing the cultural revolution that would come to a head in the 1960s and 1970s. It represented a break from the past, much like the automobiles and suburban sprawls that were reshaping the American landscape, signaling a move towards a more open, and contested social order that dared to challenge the tyranny of government overreach through an ever-expanding American empire that, similar to the past twenty years, cared more about influencing other parts of the world through chaos and strife as “foreign policy” than the well being and prosperity of citizens of the homeland.

Above: 1902 | Below: 2023 — A new fountain was unveiled in Vienna that was not commissioned by the city through local kindergartners.

Musical genres, as diverse and rich as they are, can be incisive indicators of the cultural and moral compass of a civilization.

Punk rock which emerged in the 1970s to displace disco was the reacationary sound of raw discontent. It was a visceral response to what was perceived as a bloated and hypocritical establishment during a period of economic and social decay. This musical critique set to driving power chords, echoing a generation’s frustration with a society that felt uniform and unchanging, dark and sometimes hopeless. Perhaps the punk movement also sought to test the limits of extreme grime and overt shock, for the sake of evolving music culture along the paths that preceded it.

In stark juxtaposition, music from the classical period, composed by the likes of Mozart, carried the undertones of an ordered universe. Music was ornate, highly structured, and emotionally expressive. It valued clarity, balance, and form. It echoed Enlightenment principles of symmetry, rationality, and the pursuit of perfection. This was a time when society began to place a higher value on intellectual exploration and individual human potential, and the music of the period often mirrored these ideals with its structured elegance and harmonic simplicity.

Fast forward a few centuries to genres like Hip Hop and Rap and the reflection becomes starker. Apart from early Hip Hop and Rap, today these genres have reached their terminal stages, which always seem to arrive with indulging in the glorification of wealth and conspicuous consumption. The criticism here isn’t rooted in its origins or the race and class struggle its favorable critics insist gives its roots cultural value. Those roots have degraded into the celebration of wanton excess and pornographic hedonism. The repetitive and recycled nature of both Rap and Hip Hop rarely indulge creative exploration preferring to favor monetary extraction often at the expense of emotional depth and authenticity.

Reproduction and repetition of musical pieces that lack originality or any aspiration to manifest a genuine expression reflective of a greater human experience or understanding is rejected for the cynical monotony of flexing hyper-individualist desires in a post-modern world where material displays retain all social capital, and where art need not evolve or aspire to anything beyond capturing the attention and dollars of consumers. In many ways, it perfectly encapsulates the social rot and moral decay of present-day America.

Rock and roll, in its golden age, was also a musical revolution, and some made the same accusations of decadence and decay at the time of its emergence. Still, this revolution carried a sense of breakthrough rather than breakage, representing the vitality and energy of post-war youth. Yet, as rock evolved, it too began to mirror the excesses and abundance of the society from which it sprang, and by the 1980s embraced extreme depravity with the idolatrous hedonism of rockstars becoming almost as big as their hair.

The Alternative or Grunge subgenre sought to reject this hedonism through a repackaged individualism that was more sinister and indifferent and deserted money and riches, and their material representations as signs of “selling out” to the forces of corporate dominance that spent the same decade monopolizing nearly every industry, including musical production and distribution toward its final popular resting place.

Music has the power to be the soul’s mirror to society for any given decade, revealing through its shifting styles and themes whether a civilization is ascendant and aspirational or hopelessly demoralized and incessantly digging its own grave and anything in between.

Music has long been recognized as a potent catalyst for a common cultural experience, weaving individuals toward shared emotion and connection. The concept of “collective effervescence,” as described by sociologist Émile Durkheim, captures the essence of communal bonding that occurs during concerts.1 The live music experience acts as a conduit for this phenomenon, leveraging the mirroring capabilities of our neurons, which activate not only when performing actions but also when observing others.2 This neural mimicry can lead to “emotional contagion,” to describe the synchronization of shared feelings within a group.3

Studies on the neurochemical impact of music highlight how the shared experience can trigger the release of dopamine, a neurotransmitter linked to pleasure and reward.4 The physical act of moving in rhythm with others during a live performance also fosters a sense of unity and amplifies emotional states.5 This synchronization of movement and rhythm can deepen the connection between individuals, reinforcing the collective experience as trance-like and even hypnotic.6

Marshall McLuhan’s famous saying, “The medium is the message” argues that different communication mediums ( print, radio, television, the internet) have unique characteristics that shape how people perceive and interpret information. The medium influences the way people think and interact with the content.7

While his sentiment still stands, it applies more appropriately to media and information than the technologies transforming art and culture. McLuhan died in 1980 and never lived past the analog era to see just how greatly new mediums like the Internet and digital technologies would transform not just how people perceive and interpret information prepared for their consumption by powerful forces, but how they experience and engage with cultural products, especially music.

The arrival of the digital age greatly transformed how all culture was produced, promoted, distributed, and consumed, from music, and film, to millions of podcasts that nobody listens to, and finally to what you are reading here—a combination of academic and creative writing for the distribution of ideas.

Digital Interlude

Before we continue along to that technological point that transformed music, let it be known I have no misconceptions about the power of the Internet and the innovations that have sprung from this global network. In less than two years I have been blessed to build this Substack to a low five-figure readership with no promotion on Social Media, and no money allocated for marketing or advertising. The Internet, and specifically this wonderful community on Substack, free from censorship due to its subscription model, has made it possible to share my written thoughts with others. I’m still humbled that others are interested in reading my words. Should these particular words bring value to your life, I hope that you will honor me with your patronage, or share that value with others.

While the digital technological transformations may have democratized cultural production and accelerated access to distribution, bypassing traditional anointed gatekeepers of culture, often overly educated critics living in a few major metropolises, it has also had a deleterious effect on how society consumes music, obliterating the aforementioned connections that could only arise from synchronous consumption that births collective cultural milestones.

If the medium is the message with music, the technological medium that produces, distributes, and broadcasts digital music has delivered a message that this new system dilutes the human experience which conversely degrades any aspiration to produce great works. The new digital marketplaces that have democratized production and distribution, favor quantity and fractional payments that have killed the album experience and ushered in the singles era.

Musical production has atomized consumers, shattering any euphoric shared experiences into a million different movements with no singular genre standing as a bastion of accurate cultural representation. Perhaps that old Seinfeld adage—a show about nothing—is the only true barometer of this musical epoch.

The quality of a civilization’s culture is not always in direct proportion to how that civilization rewards cultural production, but a civilization that moves from enormous incentives for popular musical production to fractions of that within a matter of years, will disincentivize and thereby decrease the pool of viable producers.

For example, when teenagers were asked what they wanted to be when they grew up in the United States in the 1960s through 1990s, many would have responded in that predictably superficial way only a mass consumer society that worships money and celebrity would—as a rock star.

Fast forward just one generation and the money and celebrity haven’t changed, but the superficial aspiration has morphed into something far more shallow, requiring no talent, charisma, or creative spirit—a YouTube star.

At least the former was rewarded much greater, had to leave home to work (tours), and knew how to play musical instruments and write songs that captured the imagination.

Today the YouTube streamer steals the music produced by yesterday’s rock stars while doing nothing that adds anything of value to the culture while talking to someone called “Chat.” There is no human connection between those viewers experiencing this stream of nothingness. Any interesting or revolutionary ideas from “YouTube Stars” are more likely to result in censorship, demonetization, and expulsion from the platform.

From Royal patronage commissioning court composers to the phonograph, radio, vinyl, 8-track, cassette, and compact disc, to where we are today, musical compensation of artists peaked in the 1990s, and while the democratization of production and distribution has allowed for greater participation in musicians accessing fans, the amount of compensation has plummeted to indecent poverty, even at the top tier. There is no way to effectively gauge how much the digital transformation of musical distribution has pilfered from musical artists via copyright infringement through outright piracy.

Compare the radio compensation model of the 1950s to the streaming compensation model of corporate tech monopolies. Let’s say Elvis’ Heartbreak Hotel was played 4x per day on roughly 500 national radio stations at the apex of its popularity. That’s 60,000 plays per month at a minimum of .04 cents per play, which came to $2500 per month. If Radiohead’s song Creep is streamed ten million times per month nearly thirty years since its release at a payment of .00034 cents per stream or sometimes nothing, with no transparent ledger of accounting besides the word of Silicon Valley thieves, it pays the band $3400 in today’s money.

Adjusted for inflation Elvis made $24,000 from radio play in today’s dollars, and there was no way anyone could pirate his music with replication technologies. He made even more through vinyl sales. Creep has probably been stolen tens of millions of times through digital piracy costing each band member millions of dollars, but according to digital age accolytes they’re supposed to be grateful that their music is being stolen because it helps them “find a new audience.”

This brings us to the defining techno-social differences affecting culture and musical consumption in the digital versus analog era.

Analog: synchronous and symmetrical | connected and shared

Digital: asynchronous and disparate | disconnected and shattered

This shift created an atomized music culture while dispensing all shared connections music once supplied. Much of our twenty-first-century world has robbed humanity of shared experiences—a glue that undergirds social cohesion and togetherness.

In the 1980s lines would form around the block of every Tower Records in the United States when a popular artist released a new album. The promotion and music videos released in advance of the album created a buzz. Friends would line up together, purchase a cassette or Vinyl, sometimes both, and then maybe return to someone’s home, or sit and park and listen to the album on cassette in a car—together.

Today nobody gets together to acquire musical works of any genre. Everyone is alone, clicking a “buy” button, or running their piracy torrent software to steal from musical artists.

If every individual is fragmented and isolated to experience their own thing alone—usually tinny-sounding digital singles—then the music culture is simply that Seinfeld irony—nothing at all.

To be clear there is a popular music culture in the twenty-first century, but perhaps it represents no culture, signifies no struggle, aspires to no greatness, breaks no barriers, defies no authority, communicates no beauty, connects no society, shares no wisdom, and imparts no flattering reflective commentary on our world, only the aforementioned rot and decay, debauchery and hedonism.

It’s as if, sometime at the turn of the century, when the digitally disconnected transplanted the synchronous and analog, all those decades of great popular music that poured into the cultural consciousness binding society through shared creative experience, were all at once, suddenly, shut off at The Spigot.

As a graduate student and later a PhD researcher at one of the oldest universities (Jagiellonian University, 1368, Kraków, Poland) I was lucky to have an academic supervisor who is a Professor of Sociology and Cultural Studies and teaches a course on Music culture.

Born in a working-class borough of South London, Professor Garry Robson came of age during one of the greatest periods of popular music—the 1960s and 1970s and experienced first-hand the bands of the British Invasion before and after they invaded America.

A few times each year a different person in our small circle in Kraków hosted a YouTube party, which had nothing to do with YouTube and everything to do with embracing the platform’s last ounce of usefulness—listening to music and watching old music videos, together, as a shared experience. These gatherings lasted sometimes late into the morning hours, without anyone noticing. The keyboard moved around the room and each person chose one or two songs before it reached the next person and so on.

While the surface goal was to experience great music together, in a social setting, it also became a kind of game, of throwing off the others, of shifting the trajectory toward something unexpected yet very much a splendid surprise. Instead of a single DJ curating a musical set, we were four or five DJs curating a musical experience with spontaneity and serendipity.

While any music was fair game, for every fifty songs chosen from the 1950s through the 1990s there was maybe one song chosen after the year 2000, and it usually involved an artist that ascended in a pre-Y2K decade.

One early morning at my flat, a few hours before sunrise it was just Professor Robson and I refusing to allow the music to stop, passing the keyboard wirelessly connected to the TV back and forth when I asked the obvious question— “Why after decades of consistently great music does most music suck after the turn of the century?”

He mentioned the Spigot, and how at some point “they shut it off.”

I re-ask the Good Professor this question in Episode #3 of Good Citizen Radio Bleats “The Spigot,” so tune in to hear his thoughts on why he believes this happened.

The absence of the power of a shared music culture to bring people together today (outside of concerts) signifies a profound loss that millions of people, particularly of older generations, deeply sense but cannot accurately understand or describe.

They only know that at some point the music stopped, and the spigot was closed.

A society that has nothing new or innovative to offer in terms of music culture in the present will see generation after generation constantly looking to the past, either out of inspiration, or nostalgia.

They will seek out music that once represented a culture, signified a struggle, broke down barriers, aspired to greatness, defied authority, communicated profound beauty, connected people, shared wisdom, and imparted some reflective commentary on a world that was less anesthetized, less demoralized, more dynamic and vibrant, one that they wish was still around but will never return.

Perhaps that’s our music culture now—reliving the glory of past music cultures and sharing it with others.

And that’s why I add at least one song to compliment every post here.

Immortal Beloveds, ever yours, ever mine, forever.

Thank you for sharing

Visit shop.thegoodcitizen.live

1. Use your affiliate link for either Healing Support promo or for Heartmend promo.

https://floralive.com/?aff=24

2. When the customer enters the floralive site (thru your link) they must add EITHER

A. add 3 Healing Support (combination essence) and 3 Blue Eyed Grass to the shopping cart, then go to checkout and enter the coupon code for this promo which is: HSHOLIDAYS  (not case sensitive).

This will charge them for the Healing Support and they will get the Blue Eyed Grass free 

Or

B. Add 6 Heartmend to shopping cart, go to checkout, there will be a charge for 4 Heartmend and two free when the coupon code  HMHOLIDAYS   is used.

Torkin Manes’ reflections on the Cannabis Act review final report

Torkin Manes’ reflections on the Cannabis Act review final report

As pretty much everyone in the industry knows, the Cannabis Act came with a baked in review clause that requires the government to review the legislation, its administration and operation within three years of the Cannabis Act coming into force.

Section 151.1(1) if the Cannabis Act sets out this requirement. Notably, it explicitly provides that the review shall include a review of the impact of the legislation on public health, and in particular, on the health and consumption habits of young persons in respect of cannabis use, the impact of cannabis on Indigenous persons and communities, and the impact of the cultivation of cannabis plants in a dwelling-house.

An expert panel, appointed by the government for this purpose, recently published a summary of the results of their initial engagement. The expert panel still has to conduct a “second phase” of its mandate, which will see it re-engage stakeholders in various discussions to “gain a deeper understanding and fill any knowledge gaps from our first phase.”

So while there is still much work to be done before the panel’s final report is prepared and ultimately tabled in parliament by March, 2024, it is fair to say that the initial findings set out the overarching framework under which the report will ultimately be based.

Advertisement

This article will only discuss the initial findings at a very high level and only those that (arguably) relate directly, or indirectly, to business considerations.

It will likely come as no surprise that there is somewhat of an inherent conflict between public health considerations and economic/business considerations. Indeed, the panel noted that “where as public health stakeholders advocated for the need to maintain a precautionary approach to cannabis in order to protect public health and safety, industry representatives asserted that a viable industry is a necessary precondition to maintain a safe and legal source of supply and to combat the illicit market.”

This is not to say that the legislative regime cannot accomplish supporting both public health and economic/business interests concurrently, but rather that in some instances there is clearly a degree of trade-off that is required. There are a few examples of this throughout the expert panel’s recent report.

Public health stakeholders indicated that there should be a focus on reducing harms associated with consumption, high-potency products, higher-risk product formats, polysubstance use and cannabis poisonings of children, amongst other things. While this group is generally supportive of the 10mg THC cap on products, there were some calls for further restrictions such as stricter age limits, setting minimum pricing for retailers and restrictions on selling flavoured products.

Not surprisingly, these suggestions run counter to those provided by industry representatives, who noted that precautionary elements of the legislative regime already make it exceptionally difficult for them to compete with the illicit market. Indeed, some stakeholders have been calling for an increase to the 10mg THC cap for some time, and would also like to see packaging and advertising restrictions loosened, in large part so that industry participants can better compete with the illicit market.

While some points, such as the THC cap limit on products, resulted in divergent opinions between public health stakeholders and industry stakeholders, other public health considerations, such as the greater need for public education and treatment efforts can clearly be supported by all sides.

Interestingly, the expert panel explicitly noted that although the objectives of the Cannabis Act did not include economic, social and environmental considerations, they heard a great deal about the economic condition of the legal cannabis market, and correspondingly devoted a fair amount of effort outlining what they heard.

Industry stakeholders expressed concern that companies in the legal market continue to struggle to realize profits and maintain financial viability. This concern was, according to feedback, attributable to direct financial considerations (such as the burden of taxes, mark-ups, fees and regulatory compliance costs), a cumbersome regulatory regime (i.e. that licensees have to content with regulatory requirements at the federal, provincial/territorial and municipal levels) and indirect financial considerations (such as THC cap limits, restrictive rules on promotion, packaging and labelling). Respondents noted that it appears that these concerns are driving smaller producers and entities out of the legal market, and either back to the illicit market or out of business altogether, thereby increasing the risks of a future market that is consolidated and dominated by a few large entities what wield significant market power.

What can we therefore expect when the final report is (hopefully) tabled in March, 2024?

On one hand, the expert panel explicitly noted that the objectives of the Cannabis Act do not include economic considerations. On the other hand, it is clear that those considerations were voiced strongly and widely. We can therefore assume that the final report will contain a fairly detailed finding of what the expert panel heard as it relates to economic considerations. The question is whether those concerns will cause the government to act on any of them in any meaningful way?

I suspect that the decision will ultimately come down to whether or not the government believes that the economic considerations are such that they actually pose a significant risk to harming the industry in general and strengthen the illicit market, which the government tis trying to eliminate. If the concerns are viewed in this light, the economic considerations clearly do tie into the other stated objectives of the Cannabis Act. However, if the government fails to appreciate the severity of the economic considerations raised and does nothing, it may find itself down the road having a far more difficult time addressing the stated objectives of the legislation.

New study suggests cannabis users may have greater “emotional comprehension”

New study suggests cannabis users may have greater “emotional comprehension”

A study published in the Journal of Neuroscience earlier this month found that cannabis users have greater emotional comprehension, a form of cognitive empathy.

While some medical professionals associate cannabis use with causing negative mental health and behavioural outcomes, this study found that cannabis users have a greater understanding of the emotions of others and that parts of the brain associated with empathy are stronger among those who use cannabis.

These findings, say the researchers, help to highlight positive effects of cannabis on interpersonal relationships and its potential therapeutic applications.

“We believe that the differences shown by regular cannabis users in the emotional comprehension scores and their brain functional connectivity, could be related to the use of cannabis. However, we cannot discard that such differences were present before the users started their use of cannabis.”

The study involved a group of 85 regular cannabis users alongside a control group of 51 non-users. The groups excluded those with neurological disorders, use of psychopharmaceuticals, depression, and MRI contraindications. 

Researchers “applied the Cognitive and Affective Empathy Test (TECA, in Spanish), developed by López-Pérez and Pinto, which analyzes the empathic ability of the subject, assessing both cognitive and affective empathy.” MRI scans were also used to assess brain activity in areas associated with empathy. 

The psychometric tests showed that cannabis users scored higher in emotional comprehension than non-users. They caution, however, that it’s possible the cannabis users they observed in the research were more empathetic prior to consuming cannabis.

The study also noted that the quality of cannabis consumed in Mexico is often around 2%–10% THC on the illegal market, much lower than cannabis consumed in legal markets in the US or Canada. Researchers caution this could lead to different results when using higher-potency cannabis.

The differences in THC concentrations between US and Mexican cannabis could have a differential impact on functional brain outcomes between the present study and those reporting emotional dysfunctions in cannabis users.  

The results of the MRI tests indicated that “regular cannabis users showed greater connectivity between the anterior cingulate cortex (ACC) and the pre-posterior central gyrus (pr-pCG). In the within empathy network analysis, the users showed greater connectivity between the left anterior insula (lAi) and the ACC, and greater network strength when compared to controls (t = 2.27, p = .02).”

The authors note that “the ACC is a region that is prone to the effects of cannabis consumption and is also greatly involved in empathy, which is a multi-component process that can be influenced in different ways. In the present study, regular cannabis users scored higher on emotional comprehension when compared to non-users.” 

“We believe that the differences shown by regular cannabis users in the emotional comprehension scores and their brain functional connectivity, could be related to the use of cannabis. However, we cannot discard that such differences were present before the users started their use of cannabis.”

They continue, saying that “this difference is consistent with those reported by Vigil et al., where cannabis users report a higher ability to detect others’ feelings compared to non-users. Additionally, previous research has shown that these types of psychometric results correspond with the subjective experience and behaviours of cannabis users related to a greater understanding of other emotions, less verbal hostility, enhanced prosociality and empathic predisposition to others’ situations.”

In closing, they hypothesize that they “believe that these results contribute to open a pathway to study further the clinical applications of the positive effect that cannabis or cannabis components could have in effect and social interactions.”