by Grow Up Conference | Oct 19, 2023 | Grow Up News
October 16, 2023, Victoria (BC): After a successful show in Victoria, BC, attended by more than a thousand cannabis industry leaders, hosting the first onsite cannabis sampling in BC and an interview with the iconic Tommy Chong, Grow Up has announced the inaugural Top 40 Cannabis Leaders in Canada 2024.
The Top 40 list will recognize influential leaders in the cannabis industry who are trailblazers in the growth, development and innovation of the cannabis industry, and celebrate their relentless, courageous, and innovative dedication to elevate the industry.
“The cannabis industry is brimming with talent, passion and expertise, and we’re excited to recognize the innovators, trailblazers and dedicated industry members who are truly building the foundation for the future of cannabis,” says Randy Rowe, President of Grow Up Conference & Expo.
Leaders can be nominated now through the Grow Up Conference website, with submissions closing on December 15, 2023. A judging panel will carefully review all applications, with winners to be announced in January 2024.
Cannabis industry professionals are invited to self-nominate or nominate a staff member or colleague. Nominees must be a Canadian citizen, landed immigrant or resident, and Canadians working around the globe are eligible.
A leader can be a person in any cannabis industry role who has been instrumental in the success of a business, product or initiative. Retailers, growers, business experts, owners, managers, investors, budtenders, innovators, technology gurus, educators, researchers, and other active cannabis leaders qualify as a potential nominee, no matter how extensive their history in this space may be. Only members of the cannabis industry will be considered eligible.
The final list may also include individuals not nominated, as decided in confidence by Grow Up.
The nominees will be notified by January 1, 2024, and must keep their inclusion confidential until the official announcement of the Grow Up Top 40 Cannabis Leaders in Canada 2024. Each nominee will be asked to provide additional information.
In addition, the 2023 Grow Up Industry Award Winners were announced on Sunday October 1, with Ted Smith, Victoria Cannabis Buyers Club, receiving recognition for his unwavering dedication to cannabis and patients with a lifetime achievement award, Tommy Chong was the recipient of the Legends of Cannabis award, and Vancouver Island retailer, Violet Wild Cannabis Co, awarded as Independent Retailer of the Year, presented by Weedpool.
For a full list of winners, please visit Grow Up here.
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About Grow Up Cannabis Conference & Expo:
Established in 2017, Grow Up Conference & Expo has been hailed a top cannabis industry event in Canada, hosting events in Niagara Falls, ON, Victoria, BC, and Edmonton, AB. With decades of experience creating nationally renowned high-profile events, trade summits and shows around the world, Grow Up is committed to bringing forward-thinkers, trailblazers and experts together. For more information, visit growupconference.com.
For further information and image requests, please contact:
Kaya Arai | Nine Point Agency | kaya@ninepointagency.com
Melissa Verdicchio | Nine Point Agency | melissa@ninepointagency.com
by Grow Up Conference | Oct 19, 2023 | Cannabis News Wire, Media Partners
- Lexaria, a global innovator in drug delivery platforms, recently announced that it had entered into a securities purchase agreement with a single health-focused institutional investor
- The agreement is for the purchase of 1,618,330 shares of common stock at $0.97 per share, with gross proceeds amounting to approximately $1.6 million
- The raised funds will be integral to Lexaria advancing its operations, inching it closer to FDA approval for its patented DehydraTECH(TM)-processed CBD for the potential treatment of hypertension
- It will also help assert Lexaria’s position as a leader in the market, even as it pushes the envelope in terms of research and development of its revolutionary DehydraTECH technology
Lexaria Bioscience (NASDAQ: LEXX), a global innovator in drug delivery platforms, raised approximately $1.6 million from its latest round of investment in what will mark a significant milestone for the company. In September 2023, the company announced that it had entered into a securities purchase agreement with a single healthcare-focused institutional investor to purchase 1,618,330 shares of common stock at $0.97 per share. Maxim Group LLC acted as the sole placement agent in connection with the offering (https://cnw.fm/TNjLB).
The warrants will become exercisable six months from issuance, expiring five and a half years from the issuance date. These shares of common stock were offered pursuant to a shelf registration statement on Form S-3 (File No. 333-262402), declared effective by the U.S. Securities and Exchange Commission (“SEC”) on February 4, 2022.
This move follows Lexaria’s ambitious steps to steadily advance its patented DehydraTECH(TM) technology across different areas of application, including, but not limited to, oral nicotine, antivirals, human hormone therapy, hypertension, and diabetes. Within the first half of the 2023 calendar year, the company had significantly scaled up its research and development (“R&D”), with a primary focus on the execution of hypertension, oral nicotine, and diabetes studies (https://cnw.fm/Cfdmo). Each of these studies yielded positive and promising results, ultimately setting the company up for success and continued to prove the viability of its technology.
Lexaria is now closer than ever to submitting its Investigational New Drug (“IND”) application for its planned U.S. Phase 1b Hypertension Clinical Trial with the U.S. Food and Drug Administration (“FDA”). Similar levels of success have been replicated in other studies, with the DIAB-A22-1 pre-clinical diabetes study showing that DehydraTECH-processed CBD yielded successful results showing positive impacts on blood glucose levels, overall body weight, locomotor activity, as well as triglyceride and blood urea nitrogen levels.
The raised funds will be integral to Lexaria further advancing its operations, specifically its research, inching it even closer to FDA approval for its DehydraTECH-CBD for potential hypertension treatment. In addition, it will help assert its position as a leader in the market, all while creating value for its shareholders.
For more information, visit the company’s website at www.LexariaBioscience.com.
NOTE TO INVESTORS: The latest news and updates relating to LEXX are available in the company’s newsroom at https://cnw.fm/LEXX
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by Grow Up Conference | Oct 19, 2023 | Cannabis News Wire, Media Partners
Eligible Canadian marijuana cultivators and processors can seek financial support through the new Sustainable Canadian Agricultural Partnership program (Suitable CAP), valued at C$3.5 billion ($2.6 billion). The program could bring relief to the smaller players in Canada’s marijuana industry that have been grappling with continuous deflationary pressures and intense competition, coupled with limited access to funds from private-sector lenders.
The support provided by the Sustainable CAP will be an addition to various other federal funding sources that Canadian marijuana companies have been leveraging. These include the National Research Council Canada (NRC), the Industrial Research Assistance Program (IRAP), and the Scientific Research and Experimental Development (SR&ED) program. The Sustainable CAP program is a collaborative effort between the federal and provincial governments under the umbrella of Agriculture and Agri-Food Canada, the governmental department responsible for agriculture.
George Smitherman, CEO of the Canada Cannabis Council, expressed satisfaction with the initiative, describing it as a significant shift in the agricultural department’s acknowledgment of cannabis as a value-added agricultural product. The council serves as the national industry association, representing the interests of numerous licensed processors and producers in the country.
Replacing the Canadian Agricultural Partnership (CAP), the Sustainable CAP program will be operational from April 1, 2023, until March 31, 2028. It comprises a C$1 billion allocation for activities and programs directly managed by the federal government, with an additional C$2.5 billion committed to cost-shared programs overseen by territories and provinces.
Until now, no marijuana companies have been involved in federal projects under the Sustainable CAP.
One of the federal programs of Sustainable CAP that marijuana-related enterprises may qualify for is the AgriAssurance Program, which includes two segments: the Small and Medium-Sized Enterprise (SME) and the National Industry Association (NIA). The NIA segment finances projects at the national level to facilitate the industry in creating and adopting tools, standards and systems that bolster safety and health claims pertaining to agricultural and agri-food Canada products. The SME segment aims to aid for-profit SMEs in executing assurance projects that cater to market and regulatory prerequisites.
Cannabis businesses are eligible to seek funding from both the AgriScience and AgriInnovate programs, provided that their proposals align with the program’s objectives, they possess valid licenses and their activities are consistent with their Health Canada licenses.
Applications for Sustainable CAP programs are evaluated on an individual basis, contingent on the specific program’s funding criteria. Additionally, applicants must already possess the requisite licenses and comply with federal and provincial laws and regulations, including the Cannabis Act.
Licensed operators such as TerrAscend Corp. (TSX: TSND) (OTCQX: TSNDF) could be pleased by these developments that show that the cannabis industry is now being embraced as any other industry that needs to be supported in any way possible so that it can thrive not just nationally but on a global scale too.
About CNW420
CNW420 spotlights the latest developments in the rapidly evolving cannabis industry through the release of two informative articles each business day. Our concise, informative content serves as a gateway for investors interested in the legalized cannabis sector and provides updates on how regulatory developments may impact financial markets. Articles are released each business day at 4:20 a.m. and 4:20 p.m. Eastern – our tribute to the time synonymous with cannabis culture. If marijuana and the burgeoning industry surrounding it are on your radar, CNW420 is for you! Check back daily to stay up-to-date on the latest milestones in the fast -changing world of cannabis.
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by Grow Up Conference | Oct 18, 2023 | Media Partners, Stratcann
A restaurant in Edmonton is now serving cannabis-infused food and drink on an invitation-only basis through a partnership with a local licensed cannabis producer.
CBD CBN is the name of a new business offering infused products, utilizing a Health Canada research licence held by Token Naturals, a licensed cannabis producer located in Edmonton.
Co-owner of CBD CBN (Catering By Day, Catering By Night), Stacey Mison, says it’s a small restaurant space with room for about 20 guests to sit at a long family-style table or the bar. Their menu is created based on input from their guests, focusing on the different flavours of cannabis more than any intoxicating effect.
“We get to know who our guests are—their tolerance levels, if they’ve been consuming a while or if they’ve never consumed at all—and just figuring out how to usher them through an experience that they’re going to enjoy,” she explains to StratCann.
“A lot of what we’re doing is looking at it more from a flavour perspective of the different cannabis plants and terpene profiles they offer. So looking at it as a culinary ingredient, not just something that gets you stoned.”
Guests to the restaurant need to sign a waiver before enjoying any of the dishes at CBD CBN. They can also complete a questionnaire afterward about their experience, a process similar to other research licence holders in Canada.
“It allows for education,” Mison told City News recently. “It allows for conversations. It allows a place for people to gather and have the conversations that haven’t been happening so we can keep moving forward and show the rest of the world as more of the world becomes legal that this is what we can be doing and this is the way forward.”
Keenan Pascal, CEO of Token Naturals, says he and his team were first approached by Stacey and her partner James Mulholland earlier this year, an opportunity Pascal was eager to participate in.
“We were approached by Stacey and James in June of this year. We had attended some of their previous infused dinners and were connected through the general industry. When the opportunity arose to expand the cannabis landscape in our hometown with capable partners, we jumped on it.”
Pascal explains that Token first received their research licence for cannabis in late 2021. Then, at the end of August, their licence amendment was approved, expanding their research licence area into the restaurant space, which allows the company to possess cannabis for the purpose of research and to transport, send or deliver cannabis between the facility and the restaurant.
“As a manufacturer of drinks and edibles and more, we’re specifically looking at research on palatability and taste, along with qualitative information on the experience of ingesting cannabis-infused beverages and food,” he tells StratCann.
“This is under the larger umbrella of human sensory analysis. The pairing of culinary and alcohol-free beverages aligns perfectly with Token’s lines of cannabis products and with the mocktails of our sister company, Token Bitters. We’re also looking at this as less formalized research around cannabis consumption venues and how they might add to the larger landscape of Edmonton.”
Images via CBD CBN
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by Grow Up Conference | Oct 18, 2023 | Cannabis News Wire, Media Partners
Ohioans are currently voting to decide the fate of a proposed initiative aimed at legalizing recreational marijuana. Early voting commenced on Oct. 11, 2023, with the statewide election scheduled for Nov. 7.
The initiative, which bears the designation Issue 2 on the ballots, has been championed by the Coalition to Regulate Marijuana Like Alcohol. The campaigners spent more than a year pushing for the initiative to be included on the ballot since the Republican-controlled legislature would not expand on the present medicinal marijuana policy.
Should the initiative gain approval, Ohio would become the 24th state to legalize recreational cannabis. This would supersede the existing medical cannabis program, which has steadily expanded since its inception in 2016.
The proposal encompasses provisions permitting adults 21 years of age and older to purchase and possess up to 2.5 ounces of marijuana and 15g of concentrate. Additionally, they would be allowed to cultivate a maximum of six plants, with a cap of 12 for households with multiple adult occupants.
The commercial production and distribution of marijuana products would be subject to regulation by a newly established state agency: the Division of Marijuana Control. The commission will be responsible for licensing, enforcing regulations, conducting investigations, and levying penalties on testing laboratories, operators, and other players in the recreational cannabis sector.
Recreational cannabis sales would be subject to a 10% tax, with the generated revenue allocated toward a cannabis social-equity and employment fund, the oversight of the program, support for communities hosting marijuana facilities and addiction services.
A poll conducted in July by the USA Today Network revealed that a majority of Ohio voters, approximately 58.6%, are in favor of legalization. This sentiment is more pronounced among younger respondents, with 76% of those aged 18 to 34 showing support, in contrast to 43% of individuals aged 65 and above. Additionally, another survey by Fallon Research discovered that 59% of voters were in favor of the ballot initiative, while 32% stated they would vote against it.
The law would take effect 30 days after the voting results are officially certified. However, the longevity of legalization is not assured since this is a citizen-initiated statute and not a constitutional amendment. State legislators can still repeal or amend the program following the election.
Currently, several groups, including law-enforcement agencies and the Ohio Children’s Hospital Associations, are against the initiative. Republican legislators are also against it and may become more assertive in contravening the public’s will, particularly with a favorable presidential election year in 2024.
If the measure to legalize recreational cannabis succeeds and is implemented, Ohio could see the mushrooming of not just marijuana companies but also other verticals connected to the industry in the same way that entities such as Innovative Industrial Properties Inc. (NYSE: IIPR) have carved out a niche serving marijuana companies in other state markets.
About CNW420
CNW420 spotlights the latest developments in the rapidly evolving cannabis industry through the release of two informative articles each business day. Our concise, informative content serves as a gateway for investors interested in the legalized cannabis sector and provides updates on how regulatory developments may impact financial markets. Articles are released each business day at 4:20 a.m. and 4:20 p.m. Eastern – our tribute to the time synonymous with cannabis culture. If marijuana and the burgeoning industry surrounding it are on your radar, CNW420 is for you! Check back daily to stay up-to-date on the latest milestones in the fast -changing world of cannabis.
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by Grow Up Conference | Oct 18, 2023 | Extraction Magazine, Media Partners
The exact knowledge of the metabolic pathways and factors modulating the formation of active compounds in plants is a must if you attempt to ameliorate the phytochemical profile composition, both in terms of yield and homogeneity.
The study of the plant’s active compounds biogenesis is crucial in order to understand the mechanisms that allow the formation of active compounds and the interrelationship between active compounds biosynthesis and the common cellular constituents. Moreover, the study of the formation of active compounds can help understanding their physiological role and the phytogenic relationship between different plant species.
Carbohydrates, proteins, lipids, nucleic acids, coenzymes, and vitamins are among the few substances used by living organisms in order to perform vital processes. The biosynthesis and degradation of these compounds constitute the “primary metabolism”.
Primary metabolites are typically formed during the plant growth phase as a result of energy metabolism, and are deemed essential for proper plant growth. Some examples of processes of the primary metabolism are:
The anaerobic and aerobic degradation of glucose
The synthesis of nucleic acids
The synthesis of proteins
In addition to the primary metabolites, which play a role in maintaining the viability of the plant a number of compounds such as terpenes, steroids, anthocyanins, anthraquinones, phenols and polyphenols, which belong to the “secondary metabolism”, are also synthesized. [1]
Plants secondary metabolites are produced in significant amounts, are synthesized in a precise plant organ and can accumulate in a different part of the plant, independently from their origin. To make an example tropane alkaloids are formed in the roots but can accumulate in plant leaves.
Employing marked precursors it is possible to highlight the linkage between primary metabolites and secondary ones. In fact many intermediates derived from the primary metabolism can be used by the plants to synthesize secondary metabolites. External factors can induce the plant to accumulate intermediate compounds such as fats, proteins and polysaccharides and through enzymatic or spontaneous processes it is possible to create secondary metabolites.
So these can be formed both following normal plant processes or synthesized thanks to external stimuli activating the bio-transformation.
Primary metabolites, intermediates and secondary metabolites co-exist in plants. Nevertheless the latter ones are the more interesting from a pharmacological point of view and for this reason are called active ingredients. [2]
Factors influencing the content and the quality of active compounds
The amount and entity of active compounds contained in an medicinal plant can vary greatly and can also miss completely. On the other hand, primary metabolites necessary for the plant functioning are present in enough quantities to guarantee the normal functioning of plant biological structure.
Many factors influence the content of secondary metabolites in a plant such as:
Genetic or endogen traits
Growing environment (ecologic traits)
Biotic factors (herbivores, pests, etc.)
The plant collecting period
The herbal preparation and conservation
Endogen factors
For many years the general belief was that plants belonging to the same botanical species contain the same active ingredients, and that the morphological traits are the expression of these substances.
Over time, thanks to the advancements in extraction technologies, we discovered that many plants, even if similar in morphological traits, contain and produce completely different phytochemical compounds. To make an example the plants producing eucalyptus essential oil are morphologically identical. Nevertheless the organoleptic traits of the essential oil will be completely different from plant to plant. In the same way, the Indian hemp doesn’t differentiate greatly from the European hemp, apart from the great production of resin.
For this reason, over time, many efforts have been made to select the best medicinal plant varieties among the species producing a constant amount and quality of active compounds. The amelioration of plants’ physiological and biochemical traits can be made acting at the level of their genome, thus manipulating their genetic endogenous factors.
The plant’s mass and genealogical selection, the hybridization and the plant mutations are among the techniques used today to uniform the phytochemical composition of medicinal plants.
Plants mass selection
This technique is also known as phenotypic selection and it has been widely used in horticulture. Mass selection consists in collecting the seeds from the plants having the desired appearance, creating an elite plant cultivation. Repeating this selection over the years permits constant control over plant variations and degenerations. Following this methods a mixture of pure lines is obtained. Mass selection is the simplest and least expensive of plant-breeding procedure
Genealogical selection
Also known as pure-line selection, this method permits the creation of a very large number of varieties that differ from the original strain in characteristics such as color, lack of thorns or barbs, dwarfness, and disease resistance have originated in this fashion. [3] From a genetically variable plant population, the selection of a particular plant individual and further progeny selection is made. When the differences from the initial population are not visible anymore, extensive measurement of active compounds content and quality are performed in order to obtain pure-lines with the desired characteristics. To make an example the genealogic selection allowed the increase of morphine content in the Papaver somniferum var. album reaching 18-20% compared to other varieties having just 10% of morphine content.
Hybridization
The hybridization among species with the desired trait is the dominant breeding technique in the cultivation of self-pollinating plant species. Hybridization consists in the combination of desirable plants genes creating a pure-breeding progeny superior in many aspects to the parental types. The final evaluation of promising strains involves the observation, usually in a number of years and various locations, to detect weaknesses that may not have appeared previously, the precise yield testing and the quality testing. Many plant breeders test for five years at five representative locations before releasing a new variety for commercial production.
Exogenous factors
Environmental characteristics play a crucial role in the synthesis and accumulation of active compounds in a plant. The climatic conditions can influence the plant growing stages such as vegetative period, flowering and fruit ripening. And in the same way the climate can also affect the secondary metabolites production.
Light
It has been demonstrated that the light can influence the production of active compounds in a plant. To give a few examples, the stramonium growing in full sun contains high amounts of scopolamine, 3 to 4 times higher compared to stramonium plants grown in the shade. On the other hand, Achillea plants grown in the shade will have higher production of essential oil compared to the plants of the same genus grown in the sun. Interestingly, Digitalis purpurea plants contain more cardioactive glycosides in the afternoon compared to the night period. This to say that the relation between light and plant secondary metabolites production is strictly linked to the kind of plant.
Temperature
Environmental temperature greatly influences the phytochemical composition of medicinal plants. Cold climate during the spring period can greatly reduce the accumulation of essential oil in plants such as lavender but enhance the concentration of other constituents in Matricaria chamomilla. Seeds coming from hot geographical areas can be qualitatively low compared to the ones coming from cold regions. Going from hotter to colder climates, the presence of unsaturated fatty acids increases. For this reason tropical plants contain high levels of saturated fatty acids (i.e. palm oil, cocoa butter), sub-tropical plants contain higher percentage of unsaturated fatty acids (i.e. oleic acid), plants of temperate zones contain even higher concentration of unsaturated fatty acids (i.e. linoleic acid) and the ones growing in cold areas have the complete composition of unsaturated fatty acids (i.e. linolenic acid).
Humidity level
In humid and rainy areas, plants can progressively lose their capacity of accumulating active compounds. This could be explained with the fact that water soluble constituents could be washed away from the epidermal tissues of plant aerial parts. A plant growing in a dry area tends to oxidize its oil components and this is due to the fact that oxidation products reduce the plant transpiration allowing a major resistance of the plant to the drought.
Soil texture, composition and pH
The soil texture and pH can greatly influence the accumulation of secondary metabolites in plants. Sandy, clayey or marshy soil can variate the accumulation of compounds such as essential oil or mucilage in the same plant species. To make an example, Mentha species growing in a sandy soil will accumulate a higher amount of essential oil compared to the ones grown in marshy soil. Moreover the soil composition can directly impact the final plant composition and for this reason cultivating the plant in a different habitat than the original one can completely change its phytochemical profile, and the medicinal plant could completely lose the ability to synthesize a specific secondary metabolite, losing the therapeutic action.
Biotic factors
The plants can mutually influence themselves if growing in proximity. Some studies have been made on the variations of phenotypic traits and phytochemical composition due to biotic factors. To make an example, Datura stramonium plants grown close to Lupinus species have greater concentration of alkaloids (more than 20-30%) compared to isolated grown ones. On the other hand Datura stramonium grown close to Mentha species will have a reduction of alkaloids of 50-60%.
Cell culture and synthetic production of active compounds
The incubation of cell plants in vitro permits the amelioration and protection of existing plant species, the creation of completely new species and the study of biosynthetic pathways for active compounds formation.
In vitro cell cultures are nowadays used to produce secondary metabolites and also for the creation of completely new biologically active substances. Plant cell culture technology offers a reliable and powerful production platform for continuous supply of contamination‐free, phytochemically uniform biomass from herbal, aromatic, medicinal, and even from rare and threatened plant species. [4]
After the sterilization of the material to be incubated, this can be placed on solid or liquid substrate. The second option, due to the variety of methods used such as cell culture on liquid stationary phase, periodic immersion or permanent immersion, is particularly versatile to different experimental purposes. Independently from the kind of soil used, it is important to have an initial critical number of cells in order to permit them the proliferation. The soil composition is important also in cell culture and it must contain in appropriate concentrations of nitrogen, salts such as calcium chloride, magnesium sulfate, potassium iodide, ferrous sulfate, etc.
The optimal cell proliferation temperature is between 25 and 30 °C, and light and oxygen are necessary for the production of active compounds from plant cells in vitro. [2]
References:
[1] Nicolas-Sebastian BOCSO and, Monica BUTNARIU. (2022). The biological role of primary and secondary plants metabolites. J. Nutrition and Food Processing. 5(3); DOI: 10.31579/2637-8914/094
[2] Farmacognosia. Farmaci naturali, loro preparazioni ed impiego terapeutico / Capasso, Francesco; R., De Pasquale; G., Grandolino; Mascolo, NICOLA DOMENICO C. FERDINANDO. – STAMPA. – (2000).
[3] https://www.britannica.com/science/plant-breeding/Breeding-self-pollinated-species#ref558183
[4] Georgiev V, Slavov A, Vasileva I, Pavlov A. Plant cell culture as emerging technology for production of active cosmetic ingredients. Eng Life Sci. 2018 Jul 15;18(11):779-798. doi: 10.1002/elsc.201800066. PMID: 32624872; PMCID: PMC6999513.
by Grow Up Conference | Oct 18, 2023 | Media Partners, Psychedelic News Wire
The federal government should ensure that psychedelic-related treatments are covered by a universal healthcare system, Democratic presidential candidate Marianne Williamson says. According to Williamson, the U.S. federal government should move to “fully legalize” certain psychedelics for medical use and ensure patients can access psychedelic treatments via a universal healthcare system.
America is currently in the midst of a drug reform wave that has seen more than 30 states legalize marijuana for therapeutic uses. With a growing body of scientific literature claiming that psychedelics can treat various mental-health conditions, activists, scientists and many mental-health professionals are now looking to psychedelics as a potential alternative to traditional treatments.
Researchers have uncovered plenty of evidence connecting psychedelics to significant mental-health benefits, connecting drugs such as LSD, psilocybin and MDMA with major improvements in mental health. Psychedelics have proven to be especially effective at providing long-term relief with minimal doses and barely any adverse side effects, a feat conventional mental-health treatments can hardly achieve.
Williamson outlined a new mental-health plan comprised of 10 proposals that she claims would help alleviate America’s record levels of anxiety, depression, toxic stress and suicide. Her plan includes fully legalizing the therapeutic use of certain psychedelic drugs and providing Americans with full coverage for psychedelic-assisted therapy.
The Democratic presidential candidate stated that psychedelic-assisted therapy with MDMA and psilocybin has exhibited “incredible promise” against conditions such as anxiety, depression, addiction and post-traumatic stress disorder (PTSD) that affect Americans in great numbers. She noted that states such as Oregon have already legalized many psychedelic-assisted therapies and that the U.S. Food & Drug Administration is on the verge of approving MDMA.
With recent phase 3 clinical MDMA trials showing that MDMA has lots of promise as a PTSD treatment, the psychedelic may receive FDA approval as soon as next year. Williamson said the United States must legalize all psychedelic-assisted therapies that have shown promise in scientific studies and ensure researchers have enough funding to carry out further psychedelic-related research.
Even though some places in the country have already legalized psychedelic-assisted therapy, it tends to be too expensive for most Americans to afford. Cost cannot be a barrier to any type of healthcare regardless of whether it involves psychedelics, Williamson stated, and the U.S. “must cover” psychedelic therapies in a universal healthcare system.
This issue seems to have bipartisan support as Republican presidential candidate Vivek Ramaswamy has also talked about allowing military veterans to access certain psychedelics to address mental disorders such as PTSD.
The growing agitation for psychedelic policy reform could be in part due to the growing body of scientific data from entities such as Seelos Therapeutics Inc. (NASDAQ: SEEL) that are conducting drug-development programs leveraging hallucinogenic substances.
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by Grow Up Conference | Oct 18, 2023 | Garden Culture Magazine, Media Partners
You are not alone if you struggle to understand perfect airflow in your room. I have designed 100+ grows, extraction facilities, and GMP spaces, and airflow is typically one of the most crucial factors in all applications. I must always consider each room and each application to determine the best options. There are many different ways to get ideal airflow. However, much of that can depend on your application and what you are trying to accomplish. As with many aspects of indoor growing, there are many ways to resolve airflow. We will start with the ideal scenario, which, unfortunately, is also generally the most expensive solution. Then, we can discuss other options and logic for solving the problem more efficiently.
Why Is Airflow Important?
Before finding ways to solve or distribute the air, we should consider why we are trying to be so specific with airflow and its effects on your rooms and plants. As with all grow rooms, airflow helps dictate the microclimates in each space. Microclimates form due to specific elements, such as moisture, cooling, dehumidification, and light sources. For a microclimate to occur in a room with good airflow, you must have something causing the issue. Proper airflow ensures that all plants see the same climate conditions and can transpire at the same rate for optimum plant growth. Places in the room that are too hot, cold, humid, or windy will cause plants to grow unequally and affect plant health. Ideally, a grow will have evenly distributed air so all plants have the same opportunity to grow uniformly.
The Perfect Situation
The perfect grow room airflow comes from the designs used in the GMP pharmaceutical world. These designs have been used for many years to create a uniform, clean room. With Stratus Designs, we have taken a twist (pun intended) to this approach, removed the typical laminar diffusers, and switched them to radial twist diffusers. The air in these applications is distributed overhead in the primary air handler. The overhead distribution for indoor growing works well, as the main sources of heat gain to the rooms are the lights. To cool space, you need to deliver air colder than you are trying to achieve. If you want 80°F in an area, you may have to deliver at 65-70°F to maintain those conditions.
The beautiful thing about overhead air distribution is we can get the heat from the lights out at the source and not have it radiate down onto the plants as much. We can also ensure we don’t have freezing air directed right onto the plants. With the radial twist diffuser, we mix the air at the source and add turbulence above the light fixtures to help break the microclimate barrier that forms. The twist diffuser successfully blends the air and creates a better growing environment. In this perfect situation, we do a low-level return (how the air gets back to the air handler), resulting in a uniform room. Bottom returns are ideal, as all the clean air comes from the top and “pushes” all the dirty air down to the low returns. The air is then sucked up and returned to the air handler for filtration, treatment, and redelivery. With bottom returns, it is essential to do about 10 feet of stainless steel duct so that when washing the floor, you don’t risk splashing water in and rusting the bottom of the duct out. With a top supply and bottom return, you will get a beautiful room with very uniform plants. While this is typically a very high-end design, I suspect some clever home growers can modify their rooms and accomplish this simpler than full, in-wall return grills.
The Price Is Right
In designing these spaces, I’m constantly asked for a more cost-effective solution to ducting distribution. From my experience, there is no substitute for bottom returns. However, we have had success with another distribution type and fans. This type of distribution is also with radial twist diffusers. However, rather than many low returns grills, we use one large return low near the back of the room or closest to the air handler. This idea saves money and room space, as walls don’t need to be 12-18″ thick to install ductwork. The issue with the single return is the front of the room often doesn’t quite get the airflow we want. In these applications, the client must install in-room fans to add supplemental movement in the spaces. I typically recommend fixed-direction fans with speed control. Renegade makes good low-cost EC (electronic current modulation) fans that are speed-controlled and energy-efficient. In these types of installs, I recommend that clients take the air and blow it to the front of the room, away from the return grill. The reason for this is the return should be the lowest pressure point in the room, which means the air tends to want to go to that side. By blowing the air to the front of your room, we can create extra movement, helping minimize microclimates. The only thing the same about all rooms is they are all different, so don’t be afraid to experiment and see how your plants behave.
I should note that I don’t like to return air from the ceiling in all applications, as it doesn’t allow proper air circulation and can often lead to short air cycling. I have done this before, and it can work, but it is not ideal.
Other Types Of Grows
The two options above are my typical design for air handler-based grows. However, what about grows with mini-split AC/Heat pumps? This type of design gets more complicated in determining the best distribution; you have little to no flexibility regarding where your supply and returns in a room go. Your only option is the indoor unit head placement and height. I always mount my mini-splits at the light height or higher. I do this as the cold air from my mini-split will fall, and I want to pick up the hot air at its source. Unfortunately, the return on the mini-split is now up high, and mixing becomes an issue again. With my mini-split projects, I try to space them evenly throughout the room and avoid microclimates by strategically placing fans. I find my handheld psychrometer (which measures temperature and humidity) to ensure my rooms are uniform. Again, I use EC fans and modulate fan speed to get the perfect plant movement.
Airflow is vital to plant health. Plants need wind to grow strong and to help mix the air in a space. Without proper airflow, you will have a hard time growing great plants. Your ladies want to dance a little to transpire just right. Make sure you spend plenty of time in a grow room during all stages of growth to adjust your fans accordingly. Good airflow means healthy plants, and healthy plants make you happy.
by Grow Up Conference | Oct 18, 2023 | Cannabis Prospect Magazine, Media Partners
by Grow Up Conference | Oct 18, 2023 | Cannabis Prospect Magazine, Media Partners
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